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Resins for solid phase organic chemistry

Product: Wang resin [Catalog # 32,010]

Description:
p-Benzyloxybenzyl Alcohol resin. The standard resin for the Fmoc batch SPPS of peptide acids. Loading: 0.60 - 1.30 mmole/g resin.



Product: HMBA-AM resin [Catalog # 17,080]

Description:
4-Hydroxymethylbenzoic acid AM resin. This support consists of aminomethyl polystyrene resin functionalized with base-labile 4-hydroxymethylbenzoic acid linker. Loading: 0.80 - 1.20 mmole/g resin.

 


Product: Oxime resin [Catalog # 24,010]

Description:
This support is useful for the synthesis of carboxamides, hydrazides and hydroxamic acids. Loading: 1.00 - 1.20 mmole/g resin.



Product: Rink Acid resin [Catalog # 27,010]


Description:
4-(2',4'-Dimethoxyphenyl-hydroxymethyl)-phenoxy resin. An acid-labile support for the Fmoc batch SPPS of protected peptide fragments. Loading: 0.80 1.20 mmole/g resin.




Product: Rink Amide resin [Catalog # 27,020]

Description:
4-(2',4'-Dimethoxyphenyl-Fmoc-aminomethyl)-phenoxy resin. An excellent support for the Fmoc SPPS of peptide amides. Loading: 0.40 - 0.70 mmole/g resin.




Product: Weinreb AM resin [Catalog # 32,020]


Description:
N-Fmoc- N-methoxy-b-alanine AM resin. This support is useful for the production of peptide aldehydes and other carboxaldehydes. Loading: 0.60 - 1.20 mmole/g resin.





Product: REM resin [Catalog # 27,030]

Description:
This support is useful for the preparation of tertiary amines. Loading: 0.80 - 1.20 mmole/g resin.




Product: p-Nitrophenyl carbonate resin [Catalog # 23,010]

Description:
Resin-bound p-nitrophenyl carbonate esters react readily with amines to provide the corresponding resin-bound carbamate. Loading of this resin can be established by measuring the release of p-nitrophenolate. Loading: 0.80 - 1.20 mmole/g resin.
 

  

Polymer matrix: Copoly(styrene-1% DVB), 100 - 200 mesh.

Storage/Handling: Room temp (+20C)

Shipping: Express Courier

  

References:

G. Lu, et al. (1981) J. Org. Chem., 46, 3433.; R. C. Sheppard, et al. (1982) Int. J. Peptide Protein Res., 20, 451.; H. Rink (1987) Tetrahedron Lett., 28, 3787.; J. A. Fehrentz, et al. (1995) Tetrahedron Lett., 36, 7871.; T. Q. Dinh & R. W. Armstrong (1996) Tetrahedron Lett., 37, 1161.; C. M. Tice, et al. (2002) Tetrahedron Lett., 43, 7491.; C. Y. Ho & M. J. Kukla (1997) Tetrahedron Lett., 38, 2799.; N. D. Hone & L. J. Payne (2000) Tetrahedron Lett., 41, 6149.; A. L. Smith, et al. (2000) Bioorg. Med. Chem. Lett., 10, 2693.; A. K. Ghosh, et al. (2001) J. Org. Chem., 66, 2161.; A. Paio, et al. (2003) Tetrahedron Lett., 44, 1867.

For laboratory use only


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Last updated: 06/20/06.