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Resins for solid phase organic chemistry

Product: Aminomethylpolystyrene [Catalog # 10,030]

Description:
These resins can be easily acylated with any appropriate carboxylic acid-containing linker using standard methods of amide bond formation to furnish supports for solid phase organic synthesis. Loading: 0.8 - 1.2 mmole/g resin.


Product: Hydroxymethylpolystyrene [Catalog # 17,070]

Description:
This resin is ideal for the solid phase immobilization of carboxylic acids. Reaction with a suitable phosgene equivalent converts this resin to a support suitable for the immobilization of amines. Loading: 0.8 - 1.2 mmole/g resin.


Product: Carboxypolystyrene [Catalog # 12,020]

Description:
This carboxy functionalized resin can be used for the solid phase immobilization of amines, alcohols and phenols. The polymer-supported carboxylic acid can be activated using standard coupling reagents, or it can be transformed to the acid chloride by treatment with oxalyl chloride or thionyl chloride. Loading: 0.8 - 1.2 mmole/g resin.


Product: Trityl chloride resin [Catalog # 29,010]

Description:
An acid-labile resin for the solid phase immobilization of alcohols, amines, sugars, imidazoles and carboxylic acids. Loading: 0.8 - 1.2 mmole/g resin.


Product: 2-Chlorotrityl chloride resin [Catalog # 12,030]

Description:
An extremely acid-labile resin for preparing peptides and partially protected peptide fragments by the Fmoc strategy. Loading: 0.8 - 1.2 mmole/g resin.
 

  

Polymer matrix: Copoly(styrene-1% DVB), 100 - 200 mesh.

Storage/Handling: Room temp (+20°C)

Shipping: Express Courier

  

References:

J. M. Stewart & J. D. Young in "Solid Phase Peptide Synthesis, 2nd Ed.", Rockford, Illinois, Pierce Chemical Company, 1984, pp. 92.; R. Frenette, et al. (1994) Tetrahedron Lett., 35, 9177.; L. T. Tietze & A. Steinmetz (1996) Angew. Chem. Int. Ed. Engl., 35, 651.; D. R. Barn, et al. (1996) Tetrahedron Lett., 37, 3213.; L. J. Wilson (2001) Org. Lett., 3, 585.; S. Porto, et al. (2003) Org. Lett., 5, 2979.; C. Chen, et al. (1994) J. Am. Chem. Soc., 116, 2661.; Z. Li & A. Ganesan (1998) Syn. Lett., 405.; Y. Guan, et al. (2000) J. Comb. Chem., 2, 297.; S. Manku, et al. (2001) J. Org. Chem., 66, 874.; D. Jönsson, et al. (2001) Tetrahedron Lett., 42, 6953.; C. A. Olsen, et al. (2003) Org. Lett., 5, 4183.; F. Peri, et al. (2000) Tetrahedron Lett., 41, 8587.; O. Kinzel, et al. (2003) J. Peptide Sci., 9, 375.; D. P. Matthews, et al. (2000) J Comb. Chem., 2, 19.

For laboratory use only


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