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Staurosporine, Streptomyces sp.

Catalog# 28,040

Product: Staurosporine

Description: A potent, cell-permeable, and broad spectrum inhibitor of protein kinases. Inhibits protein kinase A (IC50 = 7 nM), CaM kinase (IC50 = 20 nM), myosin light chain kinase (IC50 = 1.3 nM), protein kinase C (IC50 = 700 pM), and protein kinase G (IC50 = 8.5 nM). Induces apoptosis in human malignant glioma cell lines.

Molecular Formula: C28H26N4O3

Molecular Weight: 466.5

CAS Number: 62996-74-1.

Appearance: Pale yellow solid. Hygroscopic.

Purity: 97% by HPLC

Storage/Handling: Refrigerator (+4C). Protect from light.

Shipping: Express Courier

 

References: Nishimura, H., and Simpson, I.A. 1994. Biochem. J. 302, 271.; Bruno, S., et al. 1992. Cancer Res. 52, 470.  

For laboratory use only


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Last updated: 06/20/06.