Description: A lipophilic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that blocks Ras function through inhibition of farnesylation. Also inhibits glucose-induced Ca2+ signaling and insulin secretion by blocking L-type Ca2+ channels in rat islet b-cells. Inhibits cell proliferation of human smooth muscle cells.
Molecular Weight: 418.6
CAS Number: 79902-63-9.
Appearance: White solid.
Purity: > 98% by HPLC
Storage/Handling: Refrigerator (+4°C)
Shipping: Express Courier
References: Merck Index 13, 8613.
For laboratory use only