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Catalog# 28,020

Product: Simvastatin

Description: A lipophilic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that blocks Ras function through inhibition of farnesylation. Also inhibits glucose-induced Ca2+ signaling and insulin secretion by blocking L-type Ca2+ channels in rat islet b-cells. Inhibits cell proliferation of human smooth muscle cells.

Synonyms: MK-733

Molecular Weight: 418.6

CAS Number:  79902-63-9.

Appearance: White solid.

Purity:  > 98% by HPLC

Storage/Handling: Refrigerator (+4C)

Shipping: Express Courier

RTECS: EK7798000


References:  Merck Index 13, 8613.

For laboratory use only

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Last updated: 06/20/06.