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Rapamycin

Catalog# 27,050

Product: Rapamycin

Description: Anti-fungal and immunosuppressant. Selectively inhibits the phosphorylation and activation of p70 S6 kinase (IC50 = 50 pM). Exhibits strong binding to FK-506 binding proteins. Reported to induce apoptosis in a murine B cell line, to inhibit lymphokine-induced cell proliferation at the G1 phase, and to irreversibly arrest Saccharomyces cerevisiae cells in the G1 phase

Molecular Formula: C51H79NO13

Molecular Weight: 914.2

CAS Number: 53123-88-9

Appearance: Off-White solid.

Purity: 98% by HPLC

Storage/Handling: Freeze (-20C)

Shipping: Express Courier

RTECS: VE6250000

 

References:  Merck Index 13, 8202.

For laboratory use only


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Last updated: 06/20/06.