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Leupeptin, Hemisulfate

Catalog# 21,010

Product: Leupeptin, Hemisulfate

Description: Synthetic. White Solid. A reversible inhibitor of serine and cysteine proteases. Often used for the inhibition of plasmin, trypsin, papain, kallikrein and cathepsin B. No inhibition found with pepsin, cathepsins A and D, elastase, renin or chymotrypsin. Effective concentration 10-100M.

Chemical Name: Ac-Leu-Leu-Arginal, Hemisulfate                                                                                   

Chemical Formula: C20H38N6O4.1/2 H2SO4

Molecular Weight: 475.6

CAS Number: 103476-89-7

Appearance: White Solid, Hygroscopic.

Purity: Three tautomeric isomers in solution.                             

Solubility: H2O (50 mg/ml). 

Storage/ Handling: -20 C, freezer.


Risk Statements:                                                                                 

Safety Statements: S: 22-24/25


References: Merck Index. 13, 5477.

Sarin, A., et al. (1994). J. Immunol. 153, 862.

Aoyagi, T., et al. (1969). J. Antibiot. 22, 283.

For laboratory use only

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