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Forskolin, Coleus forskohlii

Catalog# 15,180

Product: Forskolin

Description: The major cell-permeable diterpene isolated from the Indian plant Coleus forskohlii. At low doses, it acts as a positive inotropic agent. At higher doses, it serves as a hypotensive and vasodilatory agent due to its actions as a smooth muscle relaxant. Inhibits MAP kinase in rat renal mesangial cells (IC50 = 25 M). Also shown to inhibit apoptosis in cerebellar granule cells and to induce apoptosis in resting human B lymphocytes.

Synonyms: 7b-Acetoxy-8,13-epoxy-1a,6b,9a-trihydroxy-labd-14-en-11-one; Colforsin

Molecular Formula: C22H34O7

Molecular Weight: 410.5

CAS Number: 66575-29-9.

Appearance: Colorless solid.

Purity: 99% by HPLC

Storage/Handling: Room temp (+20C)

Shipping: Express Courier

RTECS: QL6150000

 

Risk Statements: 21               

Safety Statements: 36

 

References: Merck Index 13, 2500 

For laboratory use only


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Last updated: 06/20/06.