Description: A cell-permeable derivative of podophyllotoxin that acts as a topoisomerase II inhibitor (IC50 = 59.2 µM) has major activity against a number of tumors, including germ cell neoplasms, small cell lung cancer, and malignant lymphoma. Induces apoptosis in mouse thymocytes and in HL-60 human leukemia cells.
Molecular Weight: 588.6
CAS Number: 33419-42-0.
Appearance: White solid.
Purity: > 97% by HPLC
Storage/Handling: Room temp (+20°C). Protect from light.
Shipping: Express Courier
Risk Statements: 22-45
Safety Statements: 26-36/37/39-45
References: Merck Index 13, 3918.
For laboratory use only