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Catalog# 14,010

Product: E-64

Description: White Solid. Effective irreversible inhibitor of cysteine proteases. Does not affect cysteine residues in other enzymes. Acts by forming a thioether bond with the thiol of the active cysteine. Effective concentration 1-10M.

Chemical Name: trans-Epoxysucciny-L-leucyl-amido (4-guanidino) butane. ; (L-3-trans-Carboxyoxiran-2-Carbonyl)-L-Leucyl-Agmatin                                                                                          

Chemical Formula: C15H27N5O5 

Molecular Weight: 357.4

CAS Number: 66701-25-5

Appearance: White Solid          

Purity: ≥ 99%                    

Solubility: DMSO (25 mg/ml) and H2O (20 mg/ml)

Storage/ Handling: -20 C, freezer, Protect from light


Risk Statements:                                                                                 

Safety Statements: S: 22-24/25


References: Matsumoto, K., et al. (1999). Biopolymers. 51, 99.

Barrett, A. J., et al. (1982). Biochem. J. 201, 189.

For laboratory use only

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Last updated: 06/20/06.