Description: Most active and highly stable glucocorticoid. Inhibits the phosphorylation of retinoblastoma (Rb) protein. Inhibits the expression of inducible but not constitutive nitric oxide synthase in vascular endothelial cells (IC50 = 5 nM). Enhances active cation transport in aortic smooth muscle cells by stimulating the Na+ - K+ pump. Induces apoptosis in human thymocytes.
Chemical Name: 9a-Fluoro-16a-methylprednisolone
Molecular Weight: 392.5
CAS Number: 50-02-2.
Appearance: White solid.
Purity: ≥ 99% by TLC
Storage/Handling: Refrigerator (+4°C)
Shipping: Express Courier
Risk Statements: 36/37/38-43-63
Safety Statements: 24-26-36/37
References: Merck Index 13, 2960.
For laboratory use only