Description: White Solid. Acts as a potent and selective inhibitor of protein phosphatase 2A. Also inhibits protein phosphatase 1 at higher concentrations. Useful for the inhibition of PP1 and PP2A during purification of phosphorylated proteins.
Synonyms: Hexahydro-3a, 7a-dimethyl-4, 7-epoxyisobenzofuran-1, 3-dione
Chemical Formula: C10H12O4
Molecular Weight: 196.20
CAS Number: 56-25-7
Appearance: White Solid
Purity: ≥ 99%
Solubility: DMSO (10 mg/ml) or ethanol (8 mg/ml)
Storage/ Handling: +20 șC, shelf, Protect from light.
Risk Statements: R: 28-36/37/38
Safety Statements: S: 45-53
References: Merck Index. 13, 1757.
Knapp., et al. (1999). J. Pharmacol. Exp. Ther. 289, 1480-1486.
Knapp., et al. (1998). Gen. Pharmacol. 31, 729-733.
For laboratory use only